Two sample MR report
CBWD1_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 16 | -0.0672000 | 0.1210334 | 0.5875075 |
| Weighted median | 16 | -0.1005612 | 0.0158290 | 0.0000000 |
| Inverse variance weighted | 16 | -0.0900818 | 0.0117667 | 0.0000000 |
| Simple mode | 16 | -0.1047311 | 0.0284796 | 0.0022404 |
| Weighted mode | 16 | -0.1038282 | 0.0264849 | 0.0013637 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.968765 | 14 | 0.7644635 |
| Inverse variance weighted | 10.004847 | 15 | 0.8194349 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0160751 | 0.0846263 | 0.8520721 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003813 | 1e-07 | TRUE | 0.0660942 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
